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Title:
ヘマトポエチン受容体、HPR1およびHPR2
Document Type and Number:
Japanese Patent JP2005507632
Kind Code:
A
Abstract:
This invention relates to human and murine HPR1 and human and murine HPR2 polypeptides, new members of the hematopoietin receptor polypeptide family; to methods of making such HPR1 and HPR2 polypeptides; to non-human mammals in which the endogenous genomic sequences encoding HPR1 and/or HPR2 polypeptides have been partially or completely inactivated; to methods of using HPR1 or HPR2 polypeptides to identify compounds that alter HPR1 or HPR2 polypeptide activities; and to methods of preparing medicaments for and/or treating conditions associated with hematopoietin receptor function.

Inventors:
Cosman, david jay
Mosley, Bruce A
Bird, Timothy A
De Boze, Robert Ef
Willie, Stephen Earl
Application Number:
JP2002532630A
Publication Date:
March 24, 2005
Filing Date:
October 05, 2001
Export Citation:
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Assignee:
IMMUNEX CORPORATION
International Classes:
G01N33/50; A61K38/00; A61K39/395; A61K45/00; A61P7/06; A61P19/10; A61P25/00; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07K14/705; C07K14/715; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12P21/08; G01N33/15; G01N33/53; G01N33/566; (IPC1-7): C12N15/09; A61K38/00; A61K39/395; A61K45/00; A61P7/06; A61P19/10; A61P25/00; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; G01N33/15; G01N33/50; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Reiko Izumiya