Title:
ヒスタミン受容体H3ポリヌクレオチド
Document Type and Number:
Japanese Patent JP2005508652
Kind Code:
A
Abstract:
Novel splice variants of the human H3 histamine receptor are described. The splice variants have deletions of portions of the N-terminal of the wild type H3 receptor. The splice variants are useful in methods for identifying agonists, inverse agonists or antagonists of histamine action at the H3 receptor.
Inventors:
Gear Lager, Michael
Yates, Stephan El
Yates, Stephan El
Application Number:
JP2003544179A
Publication Date:
April 07, 2005
Filing Date:
November 04, 2002
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
G01N33/50; A61K38/00; A61K45/00; A61P1/00; A61P1/04; A61P1/10; A61P3/04; A61P3/10; A61P9/00; A61P9/06; A61P9/12; A61P11/00; A61P11/06; A61P13/08; A61P15/08; A61P25/00; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P25/28; A61P25/30; A61P29/00; A61P37/08; A61P39/02; A61P43/00; C07K14/705; C07K14/72; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12Q1/02; G01N33/15; (IPC1-7): C12N15/09; A61K38/00; A61K45/00; A61P1/00; A61P1/04; A61P1/10; A61P3/04; A61P3/10; A61P9/00; A61P9/06; A61P9/12; A61P11/00; A61P11/06; A61P13/08; A61P15/08; A61P25/00; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P25/28; A61P25/30; A61P29/00; A61P37/08; A61P39/02; A61P43/00; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/02; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura