Title:
雌馬尿からエストロゲンを取得する方法
Document Type and Number:
Japanese Patent JP2005511703
Kind Code:
A
Abstract:
A method for obtaining an extract from a natural mixture of conjugated estrogens from the urine of pregnant mares (PMU) by solid-phase extraction on semipolar adsorption resins in which the resulting extract meets the pharmaceutical specifications for conjugated estrogens and the content of free estrogens is minimized even if old pregnant mares' urine and/or pregnant mares' urine which has been stored or transported at elevated temperatures is used.
Inventors:
Heinz-Helmer Rache
Olaf Rupp
Olaf Rupp
Application Number:
JP2003549371A
Publication Date:
April 28, 2005
Filing Date:
November 27, 2002
Export Citation:
Assignee:
Solvay Pharmaceuticals GmbH
International Classes:
A61K35/22; A61K38/22; A61P15/12; B01J20/26; B01J20/34; A61K31/56; C07J75/00; (IPC1-7): C07J75/00; A61P15/12; B01J20/26; B01J20/34
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard
Reinhard Einsel
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard
Reinhard Einsel