Title:
デフィブロチドの生物学的活性を決定する方法
Document Type and Number:
Japanese Patent JP2005512547
Kind Code:
A
Abstract:
An enzymatic method for determining the biological activity of defibrotide is described. This method, which is based on the capacity of defibrotide to potentiate the enzymatic activity of plasmin, comprises the steps of: a) bringing into contact defibrotide, plasmin and a substrate specific for the plasmin which, by reaction with the plasmin, provides a measurable product and b) measuring the amount of product formed at successive times.
Inventors:
Roberta, Porta
Franco Cattaneo
Ferro, Laura
Franco Cattaneo
Ferro, Laura
Application Number:
JP2003552997A
Publication Date:
May 12, 2005
Filing Date:
November 27, 2002
Export Citation:
Assignee:
Gentium spa
International Classes:
C12Q1/37; C12Q1/56; C12Q1/68; G01N33/48; (IPC1-7): C12Q1/37; C12Q1/68
Attorney, Agent or Firm:
Mitsuo Matsui