Title:
ソロスペルミンアナログの調製方法および使用方法
Document Type and Number:
Japanese Patent JP2005512948
Kind Code:
A
Abstract:
Psorospermin is a cytotoxic dihydroflranoxanthone that has found to exhibit significant activity against various tumor cell lines. Unfortunately, psorospermin is no longer readily available from its natural plant source. The present invention is directed to a method for preparing psorospermin and psorospermin analogs. Methods are also disclosed for utilizing psorospermin analogs to inhibit cellular proliferation.
Inventors:
Harley, lawrence
Fellows, Ingrid M.
Witten, Jeffrey Peep.
Schwabe, Michael Kay.
Fellows, Ingrid M.
Witten, Jeffrey Peep.
Schwabe, Michael Kay.
Application Number:
JP2002591509A
Publication Date:
May 12, 2005
Filing Date:
May 20, 2002
Export Citation:
Assignee:
BOARD OF REGENTS,THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
C07D311/86; A61K31/35; A61P35/00; A61P43/00; C07D493/04; (IPC1-7): C07D493/04; A61K31/35; A61P35/00; A61P43/00; C07D311/86
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita