Title:
タムスロシン錠
Document Type and Number:
Japanese Patent JP2005512997
Kind Code:
A
Abstract:
The invention relates to a pharmaceutical tablet comprising a tablet matrix having dispersed therein 0.1 to 10 mg of tamsulosin or a pharmaceutically acceptable salt thereof, and optionally having an enteric coating over said matrix, wherein said tablet is a modified release tablet and has a dissolution profile such that in each of the media SIF, FaSSIF, and FeSSIF, said tablet releases not more than 60% of said tamsulosin at 2 hours elapsed time in USP 2 apparatus using 500 ml of said media at 50-100 rpm paddle speed, to a monolithic pharmaceutical tablet, comprising 0.1 to 10 mg of tamsulosin or a pharmaceutically acceptable salt thereof, 10 wt% - 90 wt% hydroxypropyl methylcellulose, and a total tablet weight of 10 to 300 mg, to a unit dosage form for treating or ameliorating the conditions of benign prostatic hyperplasia comprising an effective amount of one or more tablets as mentioned above, and to a method for treating the symptoms of benign prostatic hyperplasia, which comprises administering to a patient in need thereof one or more tablets as mentioned above.
Inventors:
Plattus, Johannes Yang
Van Darren, France
Lemens, jacobs em
Van Darren, France
Lemens, jacobs em
Application Number:
JP2003541821A
Publication Date:
May 12, 2005
Filing Date:
November 01, 2002
Export Citation:
Assignee:
Shinton Besloten Fennaught Shap
International Classes:
A61K9/20; A61K9/26; A61K9/28; A61K9/48; A61K31/18; A61K47/02; A61K47/04; A61K47/12; A61K47/26; A61K47/32; A61K47/38; A61P13/08; (IPC1-7): A61K31/18; A61K9/20; A61K9/28; A61K9/48; A61K47/02; A61K47/12; A61K47/26; A61K47/32; A61K47/38; A61P13/08
Domestic Patent References:
| JPS629A | 1987-01-06 | |||
| JP2001114679A | 2001-04-24 |
Foreign References:
| WO1995002419A1 | 1995-01-26 | |||
| WO2001010436A1 | 2001-02-15 | |||
| WO2001074390A2 | 2001-10-11 |
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo