Title:
アジスロマイシンの湿式造粒法
Document Type and Number:
Japanese Patent JP2005515212
Kind Code:
A
Abstract:
The present invention relates to a method of forming non-dihydrate azithromycin granules, comprising mixing non-dihydrate azithromycin particles, with a granulating amount of a granulating liquid, and, optionally, with one or more excipients, to form wet granules which comprise non-dihydrate azithromycin and the granulating liquid. The granules are then dried to remove the granulating liquid. The invention further relates to a pharmaceutical composition comprising granules of a non-dihydrate azithromycin and at least one pharmaceutically acceptable excipient. The invention also relates to pharmaceutical formulations comprising granules of non-dihydrate azithromycin. The invention further relates to granules of dihydrate azithromycin wherein the granules comprises 98-100% dihydrate azithromycin and from about 0-2%, total weight, of one or more pharmaceutically acceptable excipients.
Inventors:
Fur John, Michael Bruce
Johnson, Barbara Alice
Johnson, Barbara Alice
Application Number:
JP2003554158A
Publication Date:
May 26, 2005
Filing Date:
December 09, 2002
Export Citation:
Assignee:
Pfizer Products Inc.
International Classes:
A61K9/14; A61K9/00; A61K9/16; A61K9/20; A61K9/26; A61K9/48; A61K31/7052; A61P31/04; A61P33/02; (IPC1-7): A61K31/7052; A61K9/14; A61K9/16; A61K9/20; A61K9/48; A61P31/04; A61P33/02
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama