Title:
1H-ピロロ[3,2-b]ピリジン-3-カルボン酸アミド化合物
Document Type and Number:
Japanese Patent JP2005516901
Kind Code:
A
Abstract:
Disclosed are 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid amides that bind to the benzodiazepine site of GABAA receptors. Such compounds can be used to modulate ligand binding to GABAA receptors in vivo and in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals.
Inventors:
Maynard, George, Di.
Gauche, Manuka
Audnell, Christopher, Jay.
Gauche, Manuka
Audnell, Christopher, Jay.
Application Number:
JP2003545655A
Publication Date:
June 09, 2005
Filing Date:
November 19, 2002
Export Citation:
Assignee:
Neurogen Corporation
Pfizer Products, Inc.
Pfizer Products, Inc.
International Classes:
A61K31/437; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/55; A61P25/00; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; C07D471/04; C07D519/00; (IPC1-7): C07D471/04; A61K31/437; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/55; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; C07D519/00
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda