Title:
喘息の処置におけるCCR-3受容体拮抗物質として使用するためのピペラジン誘導体
Document Type and Number:
Japanese Patent JP2005516903
Kind Code:
A
Abstract:
The invention provides compounds of Formula (I): wherein: R1-R4, A, L, and X have any of the values defined in the specification that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use, and methods and intermediates useful for preparing them.
Inventors:
Du Voice, Daisy Joe
Curtis, Dennis John
Schouglan, eric brian
Smith, david bernard
One, Bayhan
Curtis, Dennis John
Schouglan, eric brian
Smith, david bernard
One, Bayhan
Application Number:
JP2003546895A
Publication Date:
June 09, 2005
Filing Date:
November 25, 2002
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D295/12; A61K31/495; A61K31/496; A61P1/04; A61P11/06; A61P27/16; A61P37/08; A61P43/00; C07D241/04; C07D295/084; C07D295/135; C07D307/22; C07D333/24; (IPC1-7): C07D295/12; A61K31/495; A61K31/496; A61P1/04; A61P11/06; A61P27/16; A61P37/08; A61P43/00; C07D307/22; C07D333/24
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda