Title:
結晶の製造法、この方法によって得られた結晶、および得られた結晶の医薬製剤中での使用
Document Type and Number:
Japanese Patent JP2005523333
Kind Code:
A
Abstract:
The process for making crystals of a 11 beta-benzaldoxim-estra-4,9-diene derivative having an average particle size of from 3 mum to 25 mum and a maximum particle size of 100 mum, includes subjecting a supersaturated solution containing a special 11beta-benzaldoxim-estra-4,9-diene derivative of formula (I) to a wet milling by a wet milling apparatus while crystallizing, In order to obtain a primary particle suspension. Crystals obtained according to this process and pharmaceutical preparations containing them are also described and are part of the invention.
Inventors:
Grab, De Treff
Gerek, hagen
Hazel, Peter
Aichart, Anette
Greasing, Sabine
Muller, Ube
Gerek, hagen
Hazel, Peter
Aichart, Anette
Greasing, Sabine
Muller, Ube
Application Number:
JP2003587351A
Publication Date:
August 04, 2005
Filing Date:
April 22, 2003
Export Citation:
Assignee:
SCHERING AKTIENGESELLSCHAFT
International Classes:
A61K9/14; A61K31/569; A61P5/24; A61P15/00; A61P15/18; A61P17/02; A61P35/00; C07J41/00; (IPC1-7): C07J41/00; A61K9/14; A61K31/569; A61P5/24; A61P15/00; A61P15/18; A61P17/02; A61P35/00
Domestic Patent References:
| JPH04295420A | 1992-10-20 | |||
| JPH07149789A | 1995-06-13 | |||
| JP2005524698A | 2005-08-18 |
Foreign References:
| WO2001090137A2 | 2001-11-29 | |||
| US5534270A | 1996-07-09 | |||
| WO1998057648A1 | 1998-12-23 | |||
| WO2000039076A1 | 2000-07-06 |
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Makoto Onda