Title:
ポリオキシアルキレン含有ポリマー担体、モノマー及びこれらの製造に使用する方法
Document Type and Number:
Japanese Patent JP2005523962
Kind Code:
A
Abstract:
A process for the preparation of an oligonucleotide is provided. The process comprises the assembly of an oligonucleotide attached to a solid support, wherein the solid support is prepared by a process comprising polymerisation of a monomer which comprises a protected hydroxypolyC2-4 alkyleneoxy chain attached to a polymerisable unit wherein the protected hydroxypolyC2-4 alkyleneoxy chain contains from 2 to 10 C2-4 alkyleneoxy groups and wherein the hydroxypolyC2-4 alkyleneoxy chain is protected with an acid-labile protecting group, preferably an optionally substituted trityl group.
Inventors:
Moody, david john
Wellings, Donald Alfred
Wellings, Donald Alfred
Application Number:
JP2003587864A
Publication Date:
August 11, 2005
Filing Date:
April 25, 2003
Export Citation:
Assignee:
Avesia Limited
International Classes:
C07C43/205; C07H19/06; C07H19/16; C07H21/00; C07H21/04; C08F12/22; C08F12/24; C08F290/00; C08F290/06; C08G65/329; C08G65/332; C08L71/02; C12N15/09; (IPC1-7): C08F12/22; C07C43/205
Domestic Patent References:
| JPS61171712A | 1986-08-02 | |||
| JP2000504368A | 2000-04-11 |
Foreign References:
| WO2000002953A1 | 2000-01-20 | |||
| WO2001026692A1 | 2001-04-19 |
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Minako Matsuyama
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Minako Matsuyama