Title:
抗エストロゲン治療の抗心生物効果に耐性な患者における腫瘍細胞成長を阻害、阻止又は減弱するための方法及び組成物
Document Type and Number:
Japanese Patent JP2005524602
Kind Code:
A
Abstract:
Methods and kits for diagnosing tumorigenicity and for determining whether a cancer patient is resistant to the pharmacological effects of antiestrogen therapy. Increased levels of the PCDGF (GP88) growth factor are indicative of tumorigenicity and resistance to the pharmacological effects of antiestrogen therapy. The methods and kits of the invention are useful for assessing the tumorigencity of a biological sample from a patient and determining whether the patient is a candidate for antiestrogen, including tamoxifen, therapy.
Inventors:
Serero, Ginette
Application Number:
JP2003504895A
Publication Date:
August 18, 2005
Filing Date:
June 14, 2002
Export Citation:
Assignee:
A&G Pharmaceuticals, Inc.
International Classes:
A61K45/00; A61K31/138; A61K39/395; A61K48/00; A61P35/00; A61P43/00; C07K14/475; C07K16/22; C07K16/30; C12N15/09; C12Q1/02; C12Q1/68; G01N33/574; G01N37/00; A61K38/00; (IPC1-7): A61K45/00; A61K31/138; A61K39/395; A61K48/00; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Tadahiko Ito
Shinsuke Onuki
Tadashige Ito
Shinsuke Onuki
Tadashige Ito