Title:
乳房上皮細胞によるソライアシン発現を用いた方法
Document Type and Number:
Japanese Patent JP2005526233
Kind Code:
A
Abstract:
The invention features methods of diagnosing high grade ductal carcinoma in situ (DCIS) These methods involve measuring: (1) the level of HID-5 in a body fluid (e.g., blood or urine) of a subject suspected of having, or at risk of having, high grade DCIS; or (2) the level of HID-5 gene expression in breast tissue from a subject suspected of having, or at risk of having, high grade DCIS. The invention also embodies a method of inhibiting expression of HID-5 protein in DCIS cells and methods of treating a subject suspected of having, or at risk of having, high grade DCIS.
Inventors:
Polyac Cornelia
Enerbach charlotta
Enerbach charlotta
Application Number:
JP2003557518A
Publication Date:
September 02, 2005
Filing Date:
December 30, 2002
Export Citation:
Assignee:
DANA-FARBER CANCER INSTITUTE, INCORPORATED
International Classes:
G01N33/68; A61K31/7088; A61K39/395; A61K45/00; A61K48/00; A61P15/00; A61P35/00; A61P37/02; C12N5/07; C12N5/0784; C12N5/09; C12N15/09; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/574; (IPC1-7): G01N33/68; A61K31/7088; A61K39/395; A61K45/00; A61K48/00; A61P15/00; A61P35/00; A61P37/02; C12N5/06; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/574
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi
Kazunori Hashimoto
Koichi Niimi