チロシンキナーゼ阻害剤

Japanese Patent JP2005527580

A

The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.

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Kim, Anet

JP2003583339A

September 15, 2005

April 08, 2003

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MERCK & COMPANY INCOPORATED

C07D221/22; A61K31/138; A61K31/439; A61K31/4535; A61K45/00; A61P1/16; A61P3/10; A61P5/00; A61P5/02; A61P7/00; A61P9/00; A61P9/10; A61P9/14; A61P15/18; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P43/00; C07D405/06; C07D413/06; C07D471/08; (IPC1-7): C07D221/22; A61K31/138; A61K31/439; A61K31/4535; A61K45/00; A61P1/16; A61P3/10; A61P5/00; A61P5/02; A61P7/00; A61P9/00; A61P9/10; A61P9/14; A61P15/18; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P43/00; C07D405/06; C07D413/06

JP2005528387A	2005-09-22
JP2005528392A	2005-09-22

US4332810A

1982-06-01

Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura

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