Title:
500ppmより多く約3000ppmまでの水および200ppmより多く約5000ppmまでのアルコールを含有する安定ランソプラゾール
Document Type and Number:
Japanese Patent JP2005527638
Kind Code:
A
Abstract:
The present invention provides a stable 2-(2-pyridylmethyl) sulfinyl-1H-benzimidazole (lansoprazole) comprising either greater than 500 ppm and not more than about 3,000 ppm water or greater than 200 ppm and not more than about 5,000 ppm alcohol, or both. The present invention provides a method of preparing a stable lansoprozole as well as a pharmaceutical composition containing same. The present invention further provides a method of purifying lansoprazole that is substantially free of sulfone and sulfide derivatives.
Inventors:
Singer, cloud
Riverman, Anita
Beinberg, Irina
Riverman, Anita
Beinberg, Irina
Application Number:
JP2004531665A
Publication Date:
September 15, 2005
Filing Date:
November 18, 2003
Export Citation:
Assignee:
Teva Pharmaceutical Industries Limited
International Classes:
A61K9/02; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48; A61K31/4439; A61P1/04; C07D401/12; (IPC1-7): C07D401/12; A61K9/02; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48; A61K31/4439; A61P1/04
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama