Title:
血液細胞の安定化のためのホルムアルデヒド-アンモニウム塩複合体
Document Type and Number:
Japanese Patent JP2005536550
Kind Code:
A
Abstract:
A stabilization reagent composition, particularly desirable for stabilizing blood samples containing platelets, contains reactants that generate multiple species of formaldehyde-ammonium complexes; at least one inhibitor of phosphatase enzymatic activity; and at least one inhibitor of protease enzymatic activity. Blood samples and other tissues are stabilized by this composition. Such stabilized samples are produced by methods for stabilizing the tissue by contacting the sample with the composition.
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Inventors:
Maples, John A.
Charlie, Rory A.
Flagler, Daniel Jay.
Mills, Ronda A.
Richard Timmons
Charlie, Rory A.
Flagler, Daniel Jay.
Mills, Ronda A.
Richard Timmons
Application Number:
JP2004530872A
Publication Date:
December 02, 2005
Filing Date:
August 06, 2003
Export Citation:
Assignee:
Coulter International Corporation
International Classes:
G01N33/48; A01N1/02; A61K35/14; A61K47/12; A61K47/18; A61K47/42; A61K47/46; C12N5/07; C12N5/071; C12Q1/02; G01N33/49; G01N33/50; (IPC1-7): A61K35/14; A61K47/12; A61K47/18; A61K47/42; A61K47/46; C12Q1/02; G01N33/48
Domestic Patent References:
| JPH08507147A | 1996-07-30 | |||
| JPH0720128A | 1995-01-24 |
Foreign References:
| US5820721A | 1998-10-13 |
Other References:
PRINCE,H.E. ET AL: "Reduction of escapee formation in flow cytometric analysis of lymphocyte subsets", J IMMUNOL METHODS, vol. Vol.177, No.1-2, JPN6010005846, 1994, pages 165 - 173, ISSN: 0001534080
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama