Title:
化学化合物
Document Type and Number:
Japanese Patent JP2006503081
Kind Code:
A
Abstract:
Oxazole derivatives, which are useful as VEGFR2, CDK2, and CDK4 inhibitors are described herein. The described invention also includes methods of making such oxazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
Inventors:
Brown, matthew, lee
Choi, Mui
Dickerson, scott, howard
Gaussair, Cassandra
Harris, Philip, Anthony
Hunter, Robert, Neil, The Third
Pakovsky, Gregory
Peel, Michael, Robert
Stafford, Jeffrey, Alan
Choi, Mui
Dickerson, scott, howard
Gaussair, Cassandra
Harris, Philip, Anthony
Hunter, Robert, Neil, The Third
Pakovsky, Gregory
Peel, Michael, Robert
Stafford, Jeffrey, Alan
Application Number:
JP2004543799A
Publication Date:
January 26, 2006
Filing Date:
October 10, 2003
Export Citation:
Assignee:
SmithKline Beechham Corporation
International Classes:
C07D263/48; A61K31/421; A61K31/422; A61K31/427; A61K31/4439; A61K31/444; A61K31/454; A61K31/4709; A61K31/496; A61K31/5377; A61K31/541; A61K45/00; A61P35/00; A61P43/00; C07D263/30; C07D413/02; C07D413/04; C07D413/10; C07D413/12; C07D413/14; C07D417/04; C07D417/10; C07D417/12; C07D417/14; A61K
Domestic Patent References:
| JP2002528499A | 2002-09-03 |
Foreign References:
| WO2002059110A1 | 2002-08-01 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ai Fujii
Ishii Teiji
Satoshi Fujita
Ai Fujii