Title:
副作用が軽減された治療抗体
Document Type and Number:
Japanese Patent JP2006506333
Kind Code:
A
Abstract:
A therapeutic protein, such as a therapeutic antibody, that is modified with a compound that inhibits binding of the protein to its therapeutic target, thereby reducing side effects caused by the protein.
Inventors:
Waldman Hermann
Frewin Mark Raymond
Gililand Lisa Kim
Da Silva Graca Luis Ricardo Simoz
Frewin Mark Raymond
Gililand Lisa Kim
Da Silva Graca Luis Ricardo Simoz
Application Number:
JP2004522335A
Publication Date:
February 23, 2006
Filing Date:
July 23, 2003
Export Citation:
Assignee:
Isis Innovation Limited
International Classes:
A61K38/00; A61K39/395; A61P3/10; A61P9/10; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/04; A61P35/00; A61P37/02; C07K16/00; C07K16/28; C12N15/09
Foreign References:
| WO2002030460A2 | 2002-04-18 |
Attorney, Agent or Firm:
Eiji Saegusa
Kakehi Yuro
Kenji Saito
Kakehi Yuro
Kenji Saito