Title:
GERDの治療のためのMGLUR5アンタゴニストの使用
Document Type and Number:
Japanese Patent JP2006507225
Kind Code:
A
Abstract:
The present invention relates to the use of metabotropic glutamate receptor 5 antagonists for the inhibition of transient lower esophageal sphincter relaxations. A further aspects of the invention is directed to the use of metabotropic glutamate receptor 5 antagonists for the treatment of gastro, esophageal reflux disease, as well as for the treatment of regurgitation and asthma.
Inventors:
Lehman, Andaz
Mattson, Jean
Thomas, M. Storman
Mattson, Jean
Thomas, M. Storman
Application Number:
JP2004515703A
Publication Date:
March 02, 2006
Filing Date:
June 19, 2003
Export Citation:
Assignee:
AstraZeneca Akzie Borrag
NPS Pharmaceuticals, Inc.
NPS Pharmaceuticals, Inc.
International Classes:
A61K31/44; A61K45/00; A61K31/4439; A61P1/04; A61P1/08; A61P11/00; A61P11/06; A61K
Domestic Patent References:
| JP2001501604A | 2001-02-06 |
Foreign References:
| WO2001012627A1 | 2001-02-22 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Previous Patent: 青色発光トリス（８−オキソキノリン）アルミニウム（ＩＩＩ）（Ａｌｑ...
Next Patent: 薬剤、化粧品、または食品組成物の抗酸化剤として使用可能なラクトン化...
Next Patent: 薬剤、化粧品、または食品組成物の抗酸化剤として使用可能なラクトン化...