Title:
pHトリガ標的制御放出デリバリーシステム
Document Type and Number:
Japanese Patent JP2006510666
Kind Code:
A
Abstract:
The present invention relates to a novel pH triggered, targeted controlled release system. The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nano-spheres comprising pharmaceutical active ingredients that are encapsulated in a pH sensitive micro-spheres. The invention also relates to the processes for preparing the compositions and processes for using same. The controlled release system can be used to target and control the release of pharmaceutical active ingredients onto certain regions of the gastrointestinal tract including the stomach and the small intestine. The invention further pertains to pharmaceutical products comprising the controlled release system of the present invention.
Inventors:
Schaefer, Addy
Schaefer, Samuel, David
Schaefer, Samuel, David
Application Number:
JP2004559045A
Publication Date:
March 30, 2006
Filing Date:
August 21, 2003
Export Citation:
Assignee:
Salvona El Lucy
International Classes:
A61K9/50; A61K9/16; A61K9/22; A61K9/26; A61K9/51; A61K9/52; A61K31/137; A61K31/7052; A61K47/10; A61K47/12; A61K47/14; A61K47/16; A61K47/18; A61K47/24; A61K47/28; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61K47/44; A61K49/00; A61K49/04; A61K51/00; A61K9/20
Foreign References:
| WO2001051032A2 | 2001-07-19 |
Attorney, Agent or Firm:
Mikio Hatta
Yasuo Nara
Katsuyuki Utani
Ken Fujita
Masanori
Toshihiro Hasegawa
Yasuo Nara
Katsuyuki Utani
Ken Fujita
Masanori
Toshihiro Hasegawa