Title:
プロテインキナーゼ阻害剤としてのN-ヘテロシクリル置換アミノチアゾール誘導体
Document Type and Number:
Japanese Patent JP2006518368
Kind Code:
A
Abstract:
Aminothiazole compounds with N-containing cycloalkyl at the 2-amino position which are represented by the Formula (I), or a pharmaceutically acceptable prodrug of said compound, pharmaceutically active metabolite or pharmaceutically acceptable salt of said compound, or metabolite thereof, modulate and/or inhibit the cell proliferation and activity of protein kinases. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating malignancies and other disorders by administering effective amounts of such compounds.
Inventors:
Larry Andrew Alegria
Wesley Kwan Mung Chong
Xiao Song Chu
Lohit Kumar Duvadier
Linli
William Henry Romines iii
Lee Young
Ted Michael Breckman
Wesley Kwan Mung Chong
Xiao Song Chu
Lohit Kumar Duvadier
Linli
William Henry Romines iii
Lee Young
Ted Michael Breckman
Application Number:
JP2006502453A
Publication Date:
August 10, 2006
Filing Date:
February 09, 2004
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
C07D417/12; A61K31/427; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/498; A61K31/506; A61K31/5377; A61K31/541; A61K31/55; A61P9/00; A61P25/00; A61P31/12; A61P35/00; A61P37/00; A61P43/00; C07D417/02; C07D417/14; C07D471/04; C07D491/08; C07D493/08; C07D513/04
Attorney, Agent or Firm:
Yoshinobu Murofushi