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Title:
抗菌活性を有する置換されたチオフェン
Document Type and Number:
Japanese Patent JP2006519261
Kind Code:
A
Abstract:
Novel substituted thiophenes that are inhibitors of bacterial methionyl t-RNA synthetase (MRS) are disclosed. Also disclosed are method for their preparation and their use in therapy as anti-bacterial agents.

Inventors:
Jean Kyu
John Barge
Richard Jarvest
Catherine Simon Victor Friedrich
Joseph gills
Theodore M. Thalasso
Application Number:
JP2006508886A
Publication Date:
August 24, 2006
Filing Date:
February 27, 2004
Export Citation:
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Assignee:
Replica Dyne Incorporated
Jean Kyu
International Classes:
C07D409/12; A61K31/415; A61K31/4184; A61K31/4188; A61K31/437; A61K31/47; A61K31/4709; A61K31/5025; A61K31/505; A61K31/519; A61P31/00; C07D215/233; C07D235/22; C07D471/04; C07D487/04; C07D495/04; A61K
Domestic Patent References:
JP2003500397A2003-01-07
JP2002513005A2002-05-08
JP2003500395A2003-01-07
JP2006514639A2006-05-11
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita