Title:
L-セリン代謝に関与する蛋白質をコードするコリネ型バクテリアのヌクレオチド配列並びにL-セリンの微生物による産生方法
Document Type and Number:
Japanese Patent JP2006519598
Kind Code:
A
Abstract:
Nucleic acid (I), optionally recombinant and replicable in Corynebacterium, has the sequence for L-serine dehydratase (II): (a) partly or completely deleted or mutated; or (b) expressed at a lower level, relative to the natural sequence, or not at all. Independent claims are also included for: (1) gene structure (GS) comprising (I) and linked regulatory elements; (2) vector containing (I) or GS, also sequences for selection, replication in a host cell or integration into the host cell genome; (3) (II) with reduced activity, encoded by (I); (4) microorganism that contains (I); (5) probe for identification and/or isolation of genes that encode proteins involved in biosynthesis of L-serine, derived from (I) and labeled to allow detection; and (6) microbial production of L-serine by growing microorganisms of (4).
Inventors:
Peters-Vendish Petra
Netzer Roman
Eggering Rotor
Zam Hermann
Netzer Roman
Eggering Rotor
Zam Hermann
Application Number:
JP2006504233A
Publication Date:
August 31, 2006
Filing Date:
February 12, 2004
Export Citation:
Assignee:
Forschungszentrum Jürich Gesellschaft Mitt Beschlenktel Haftung
International Classes:
C12N15/09; C12N1/21; C12N9/88; C12N15/53; C12N15/60; C12P13/06; C12R1/01; C12R1/05; C12R1/06; C12R1/13; C12R1/15; C12R1/22; C12R1/365; C12R1/38
Domestic Patent References:
| JPS60120996A | 1985-06-28 | |||
| JPH11253187A | 1999-09-21 |
Foreign References:
| WO2001000843A2 | 2001-01-04 |
Attorney, Agent or Firm:
Mitsufumi Esaki
Tsuneo Mihara
Okumura Yoshimichi
Blacksmith
Tsuneo Mihara
Okumura Yoshimichi
Blacksmith