Title:
FVIIおよびFVIIaの変種
Document Type and Number:
Japanese Patent JP2006521098
Kind Code:
A
Abstract:
The invention relates to variants of FVII or FVlla comprising at least one amino acid modification in position 341 relative to HFVII or hFVIIa. The variants exhibit an increased clotting activity, i.e. reduced clotting time, compared to rhFVIIa.
Inventors:
Andersen Kim Bilbo
Repke Mass
Harning Jesper Mortensen
Glazer Steven
Repke Mass
Harning Jesper Mortensen
Glazer Steven
Application Number:
JP2006504332A
Publication Date:
September 21, 2006
Filing Date:
March 22, 2004
Export Citation:
Assignee:
Maxigen Holdings Limited
International Classes:
C12N15/09; A61K38/43; A61K38/48; A61P7/04; A61P41/00; C07K14/435; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/64; C12N15/57
Foreign References:
| WO2001058935A2 | 2001-08-16 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi