Title:
アポルフィン、及び、ケトンアポルフィン化合物とその用途
Document Type and Number:
Japanese Patent JP2006527699
Kind Code:
A
Abstract:
The invention provides certain aporphine and oxoaporphine for preparing medicine which can be used for ischemic disease prevention and treatment. The pharmacological mechanism of said compounds is to keep or increase endothelial nitric oxide synthase (eNOS), thus, the compounds can be used to produce medicines to prevent or treat mammal or human's ischemic disease, including ischemic apoplcxia, ischemic cerebral thrombosis, ischemic cerebral embolism, hypoxic-ischemic encephalopathy, ischemic heart disease or ischemic intestinal lesion.
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Inventors:
Sumeika
Lee Susung
Lee Susung
Application Number:
JP2005500673A
Publication Date:
December 07, 2006
Filing Date:
June 19, 2003
Export Citation:
Assignee:
Miki Chemical Pharmaceutical Co., Ltd.
International Classes:
C07D221/18; A61K31/473; A61P7/02; A61P9/10; C07D491/04; C07D491/06; C07D491/22
Attorney, Agent or Firm:
Seishiro Suzuki
Seishiro Suzuki
Seishiro Suzuki