Title:
抗癌治療の効力を推定するための感受性試験
Document Type and Number:
Japanese Patent JP2007501608
Kind Code:
A
Abstract:
The present disclosure provides methods for determining the sensitivity of cancerous cells to various anti-cancer therapies and predicting the efficacy of these therapies. Specifically, the present disclosure provides methods for predicting the efficacy of one or more candidate anti-cancer therapies in a patient, based on determining the sensitivity of the patient's cancerous cells after exposure to candidate anti-cancer therapies in vitro. The disclosure further provides methods for predicting the efficacy of candidate anti-cancer therapies by using an in vitro sensitivity test of the patient's cancerous cells and a surrogate in vivo efficacy test of the patient's cancerous cells grafted into a surrogate host. The disclosure further provides methods for selecting the most efficacious anti-cancer therapy(s) for a patient, thereby avoiding ineffective or unnecessary treatments.
Inventors:
Takumi Kawabe
Eitaka Kobayashi
Eitaka Kobayashi
Application Number:
JP2006522446A
Publication Date:
February 01, 2007
Filing Date:
August 06, 2004
Export Citation:
Assignee:
Canvas Co., Ltd.
International Classes:
C12Q1/02; A61K31/4745; A61K33/243; A61K45/06; A61P35/00; C12Q1/68; G01N33/50; A61K45/00; C07K7/00
Domestic Patent References:
| JP2001157585A | 2001-06-12 |
Foreign References:
| WO2003059942A2 | 2003-07-24 | |||
| WO1997046228A1 | 1997-12-11 | |||
| WO2001021771A2 | 2001-03-29 |
Other References:
藤田学園医学会誌, vol. 24, no. 2, JPN6010002293, 2000, pages 209 - 216, ISSN: 0001518385
CANCER RESEARCH, vol. 59, JPN6010002297, 1999, pages 5887 - 5891, ISSN: 0001518386
CANCER RESEARCH, vol. 59, JPN6010002297, 1999, pages 5887 - 5891, ISSN: 0001518386
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita