Title:
RAC経路のモディファイヤーとしてのMELKsおよび使用方法
Document Type and Number:
Japanese Patent JP2007502115
Kind Code:
A
Abstract:
Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MELK are provided.
Inventors:
Kadiku, Lisa
Francis, george, ross
Whore, Timothy, S.
Rigteig, kim
Francis, george, ross
Whore, Timothy, S.
Rigteig, kim
Application Number:
JP2006523383A
Publication Date:
February 08, 2007
Filing Date:
August 12, 2004
Export Citation:
Assignee:
Excelixis, Inc.
International Classes:
C12Q1/68; A61K31/7084; A61K38/00; A61K39/395; A61P35/00; C12Q1/02; C12Q1/48; G01N33/15; G01N33/50; G01N33/53; G01N33/574; A01K67/027; C12N15/09; A61K
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori