溶液中におけるタンパク質の安定化

Japanese Patent JP2007502310

A

Provided are storage containers for proteinaceous pharmaceutical compositions which are characterized in, among other things, comprising (i) a wall portion, wherein an inner wall material thereof is selected from silica-coated glass, silicone-coated glass, polymers of non-cyclic olefins, cycloolefin polymers and cycloolefin/linear olefin copolymers and (ii) one or more closure portions not constituting part of the wall portion, and which contains a formulation of a protein. Also provided are new methods of storing proteinaceous compositions. In one aspect, the stored protein is characterized as having an amino-terminal gamma-carboxyglutamic acid (Gla) domain with 9-12 Gla residues.

JPS61502941	[Title of the Invention] An electrolyte solution containing a multi-anionic substance
WO/2000/024374	CONTROLLED RELEASE LIQUID DELIVERY COMPOSITIONS WITH LOW INITIAL DRUG BURST
JP2020121997	USE OF BRAF INHIBITORS FOR TREATING CUTANEOUS REACTIONS

Jensen, Michael Beck
Hansen, Bilthe Rickegard
Kornfeld, Troels
Jacobsen, Kirsten Kramer

JP2006529638A

February 08, 2007

May 21, 2004

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Novo Nordisk Health Care Akchen Gesell Shaft

A61K9/08; A61J1/05; A61K9/19; A61K38/00; A61K38/43; A61K38/46; A61K38/48; A61K47/02; A61P7/04

JP2001500867A	2001-01-23
JPH06506601A	1994-07-28

WO2001017542A1	2001-03-15
WO2001017567A2	2001-03-15
WO2001017569A2	2001-03-15
WO2001017567A2	2001-03-15
WO2001017569A2	2001-03-15

JPN7014001233; Ｗａｉｔｅｒ　ｅｔ　ａｌ．: 'Ｐａｃｋａｇｉｎｇ　ｏｆ　ｓｅｎｓｉｔｉｖｅ　ｐａｒｅｎｔｅｒａｌ　ｄｒｕｇｓ　ｉｎ　ｇｌａｓｓ　ｃｏｎｔａｉｎｅｒｓ　ｗｉｔｈ　ａ　ｑｕａｒｔｚ-ｌｉｋｅ　ｓｕｒｆａｃｅ' Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｔｅｃｈｎｏｌｏｇｙ　Ｅｕｒｏｐｅ , 1996, ｐ２２-２７

Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama

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