Title:
ベンジルベンズイミダゾリル誘導体
Document Type and Number:
Japanese Patent JP2007505057
Kind Code:
A
Abstract:
Novel benzyl-benzimidazolyl derivatives as inhibitors of tyrosine kinases, particularly TIE-2, VEGFR, PDGFR, FGFR and/or FLT/KDR, for the treatment of tumors, according to formula (I), wherein the radicals R1, R2, r and s are defined according to Claim ( 1 ).
Inventors:
Stele, Wolfgang
Yong Tzik, Alfret
Lautenberg, Wilfried
Yong Tzik, Alfret
Lautenberg, Wilfried
Application Number:
JP2006525666A
Publication Date:
March 08, 2007
Filing Date:
August 17, 2004
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D235/30; A61K31/4184; A61K31/454; A61K31/496; A61K31/5377; A61K45/00; A61P9/00; A61P13/08; A61P15/00; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/04; A61P37/08; A61P43/00; C07D401/14; C07D405/06; C07D417/12
Domestic Patent References:
| JPH06293742A | 1994-10-21 | |||
| JPH072796A | 1995-01-06 | |||
| JP2002519412A | 2002-07-02 | |||
| JP2000281659A | 2000-10-10 |
Foreign References:
| US20020082280A1 | 2002-06-27 | |||
| US4004016A | 1977-01-18 | |||
| WO2002044156A2 | 2002-06-06 |
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata
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