Title:
分子の配置および組合せを分析する方法および装置
Document Type and Number:
Japanese Patent JP2007508643
Kind Code:
A
Abstract:
A method for the prediction of adverse cross-reactions between lead candidate biomolecules and potential reactant molecules, often biopolymers, is described. In a computational system, reactions are modeled within a suitable environment, in order to determine a reaction profile between a lead candidate molecule and a potential reactant molecule. A risk assessment is then generated for each lead based on a plurality of reaction profiles for the lead with respect to a plurality of potential reactant molecules. The method includes provision for the redesign and optimization of the lead candidate, possibly iterative in nature, in order to avoid predicted adverse cross-reactions.
Inventors:
Prakash, Adityo
Kita, debit
Fodor, Enico
Kita, debit
Fodor, Enico
Application Number:
JP2006535635A
Publication Date:
April 05, 2007
Filing Date:
October 14, 2004
Export Citation:
Assignee:
Verseon
International Classes:
G16B50/30; G06F17/50; G06Q50/00; G16B15/30; G16H10/60; G01N
Domestic Patent References:
| JPH08285757A | 1996-11-01 |
Foreign References:
| US20030036093A1 | 2003-02-20 |
Attorney, Agent or Firm:
Haruo Saito