アジド及び炭素同位体一酸化物を使用しイソシアネートを経由する、ロジウムで促進されたカルボニル化による炭素同位体標識合成の方法

Title:

アジド及び炭素同位体一酸化物を使用しイソシアネートを経由する、ロジウムで促進されたカルボニル化による炭素同位体標識合成の方法

Document Type and Number:

Japanese Patent JP2007520460

Kind Code:

A

Abstract:

Methods and reagents for rhodium-promoted carbonylation via isocyanate using carbon-isotope labeled carbon monoxide are provided. The resultant carbon isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.

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Inventors:

Langstrom, bent
Buretta, Julien
Koji Doi
Suzuki Masaaki
Ryoji Noyori
Yasuyoshi Watanabe
Karimi, Far Had

Application Number:

JP2006544582A

Publication Date:

July 26, 2007

Filing Date:

December 13, 2004

Export Citation:

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Assignee:

GE HEALTHCARE LIMITED

International Classes:

C07C263/00; A61K51/00; A61K51/04; B01J31/24; C07B59/00; C07C231/10; C07C233/00; C07C265/12; C07C269/02; C07C271/28; C07C273/18; C07C275/28; C07C333/02; C07D205/08; C07D213/64; C07D263/22; C07B61/00

Attorney, Agent or Firm:

Kenichi Matsumoto
Hirokazu Ogura
Toshihisa Kurokawa

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