Title:
リボヌクレオチドレダクターゼR2に向けられたアンチセンスオリゴヌクレオチドおよび癌の処置のための併用療法におけるこの使用
Document Type and Number:
Japanese Patent JP2007520474
Kind Code:
A
Abstract:
Combination products comprising an antisense oligonucleotide against the gene encoding a mammalian ribonucleotide reductase R2 protein and one or more immunotherapeutic agents, such as cytokines, non-cytokine adjuvants, monoclonal antibodies and cancer vaccines. The combinations can further comprise one or more chemotherapeutic agents. Methods of treating cancer in a mammal using the combinations are also provided.
More Like This:
Inventors:
Young, Aping H.
Light, Jim A.
Lee, Yoon
Light, Jim A.
Lee, Yoon
Application Number:
JP2006548057A
Publication Date:
July 26, 2007
Filing Date:
January 12, 2005
Export Citation:
Assignee:
Gene Sense Technologies, Inc.
International Classes:
A61K48/00; A61K31/7088; A61K31/711; A61K31/7125; A61K38/19; A61K39/395; A61K45/00; A61K45/06; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C12N15/11; C12N15/113; C12N15/09
Domestic Patent References:
JP2003500006A | 2003-01-07 | |||
JP2000513230A | 2000-10-10 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa