Title:
縮合複素環式化合物及び代謝調節型グルタミン酸受容体アンタゴニストとしてのその使用
Document Type and Number:
Japanese Patent JP2007523183
Kind Code:
A
Abstract:
The present invention is directed to compounds of formula: (I); wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, R1, R2, R3, R4, and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds for treating gastrointestinal disorders.
Inventors:
Martin johansson
Wensbo, David
Minidis, alexander
Starf, Karin
Cars, Anika
Edwards, Lewis
Isaac, Methvin
Stefanac, Tomislav
Slushy, Abdermalick
McLeod, Donald
Gin, tao
Wensbo, David
Minidis, alexander
Starf, Karin
Cars, Anika
Edwards, Lewis
Isaac, Methvin
Stefanac, Tomislav
Slushy, Abdermalick
McLeod, Donald
Gin, tao
Application Number:
JP2006554237A
Publication Date:
August 16, 2007
Filing Date:
February 17, 2005
Export Citation:
Assignee:
AstraZeneca Activrag
NPS Pharmaceuticals, Inc.
NPS Pharmaceuticals, Inc.
International Classes:
C07D487/04; A61K31/4188; A61K31/4196; A61K31/4985; A61K31/542; A61K31/551; A61P1/00; A61P3/00; A61P3/04; A61P3/10; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/08; A61P17/02; A61P19/02; A61P19/06; A61P21/04; A61P25/00; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P43/00; C07D487/00; C07D513/04
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita