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Title:
アミノ酸41~46に結合するモノクローナル抗体を用いたproBNPの検出方法
Document Type and Number:
Japanese Patent JP2007525427
Kind Code:
A
Abstract:
The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.

Inventors:
Kremt, Volker
Bolgia, Annelyse
Andres, Garther
Groll, Michael
Hallermeyer, Claus
Christophe Giedel
Application Number:
JP2006505419A
Publication Date:
September 06, 2007
Filing Date:
May 12, 2004
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07K16/26; C07K14/58; C12N5/10; C12N5/20; C12N15/09; C12P21/08; G01N33/53; A61K39/00
Domestic Patent References:
JP2003508724A2003-03-04
JP4834136B22011-12-14
Foreign References:
WO2000035951A12000-06-22
Attorney, Agent or Firm:
Yoshinori Hosoda