組換えパーフォリン、その発現、およびその使用

Title:

組換えパーフォリン、その発現、およびその使用

Document Type and Number:

Japanese Patent JP2007526774

Kind Code:

A

Abstract:

The present invention relates to retroviral vectors capable of driving the expression of perforin in a cell and a method of expressing recombinant perforin in a cell. The present invention also relates to recombinant perforin polypeptides and nucleic acid molecules derived therefrom and uses thereof. Also encompassed are screening assays employing such recombinant perforin molecules, compounds identified by the screening assays and uses thereof.

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Inventors:

Trapani, Joseph Albert
Smythe, Mark John

Application Number:

JP2007501057A

Publication Date:

September 20, 2007

Filing Date:

March 01, 2005

Export Citation:

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Assignee:

PETER MACCALLUM CANCER INSTITUTE

International Classes:

C12N15/09; A61K35/76; A61K38/00; A61K45/00; A61K48/00; A61P3/08; A61P3/10; A61P31/06; A61P31/18; A61P35/00; A61P35/02; A61P37/00; A61P37/06; A61P43/00; C07K14/47; C12N5/10; C12N7/00; C12N15/867; C12P21/00; C12Q1/02; G01N33/15; G01N33/50

Attorney, Agent or Firm:

Hajime Tsukuni
Fumio Shinoda

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