置換されたヘテロアリール-およびフェニルスルファモイル化合物

Japanese Patent JP2007528387

A

The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.

Hamanaka, Ernest Seiichi
Kerli, Marcus Eugene, Jr.

JP2007502428A

October 11, 2007

February 28, 2005

Click for automatic bibliography generation  

Pfizer Products Inc.

C07C311/21; A61K31/192; A61K31/22; A61K31/366; A61K31/381; A61K31/40; A61K31/404; A61K31/415; A61K31/4164; A61K31/4184; A61K31/421; A61K31/423; A61K31/4245; A61K31/426; A61K31/428; A61K31/433; A61K31/44; A61K31/4418; A61K31/455; A61K31/47; A61K31/505; A61K45/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P9/14; A61P13/12; A61P19/06; A61P19/10; A61P25/28; A61P29/00; A61P43/00; C07C311/44; C07C323/49; C07D213/75; C07D215/12; C07D231/12; C07D231/56; C07D233/68; C07D235/18; C07D263/32; C07D263/54; C07D263/56; C07D263/57; C07D271/06; C07D271/07; C07D271/10; C07D271/107; C07D271/113; C07D277/24; C07D277/26; C07D277/62; C07D277/66; C07D285/01; C07D285/06; C07D307/79; C07D333/58; C07D413/06

Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Mitsutoshi Nakamura

Previous Patent: α−ヨード−１−アゼチジン酢酸エステル及びトリアルキルホスファイト�...

Next Patent: 分子分散されたドロスピレノンを含む組成物