Title:
S1P受容体アゴニストとしての3,5-アリール置換、ヘテロアリール置換またはシクロアルキル置換された1,2,4-オキサジアゾール化合物
Document Type and Number:
Japanese Patent JP2007528872
Kind Code:
A
Abstract:
The present invention encompasses compounds of Formula I: (I) as well as the pharmaceutically acceptable salts thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
Inventors:
Doherty, Giyo A
Hale, Jefrey Jay
Regietsk, Eileen Yee
Lynch, Christopher El
Toss, Leslie M
Hale, Jefrey Jay
Regietsk, Eileen Yee
Lynch, Christopher El
Toss, Leslie M
Application Number:
JP2006533999A
Publication Date:
October 18, 2007
Filing Date:
September 27, 2004
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D271/06; A61K31/4245; A61K31/433; A61K31/4439; A61K31/497; A61P1/00; A61P1/02; A61P3/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P37/00; A61P37/02; C07D413/04; A61K
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura