Title:
融合タンパク質に基づく免疫原性組成物及びワクチンの開発方法
Document Type and Number:
Japanese Patent JP2007533646
Kind Code:
A
Abstract:
The present invention relates to an immunogenic composition. More particularly, the present invention is a composition directed to eliciting an immune response to at least one covalent binding site of myristate (SEQ ID NOS: 1-3) on the HIV matrix protein. The present invention contemplates three categories of embodiments: protein or protein fragments (SEQ ID NO: 1), messenger RNA, or DNA/RNA (SEQ ID NOS:2-3). DNA/RNA compositions may be either naked or recombinant. The present invention further contemplates use with a variety of immune stimulants.
Inventors:
Nelson M. Carp
Application Number:
JP2006536895A
Publication Date:
November 22, 2007
Filing Date:
October 25, 2004
Export Citation:
Assignee:
NK Research LLC
International Classes:
A61K38/00; A61K9/00; A61K31/715; A61K31/737; A61K35/74; A61K35/76; A61K36/06; A61K38/16; A61K38/46; A61K39/00; A61K39/02; A61K39/12; A61K39/21; A61K39/245; A61K45/00; A61P31/18; A61P37/04; C07K14/16; C12N7/06; C12Q1/70; A61K47/12; C07K14/155; C07K19/00; C12N1/19; C12N1/21; C12N7/00; C12N15/09
Domestic Patent References:
| JPH05505616A | 1993-08-19 | |||
| JPH02203793A | 1990-08-13 | |||
| JPS63207397A | 1988-08-26 |
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro