Title:
抗Wnt2モノクローナル抗体およびsiRNAを使用して癌を治療するための方法
Document Type and Number:
Japanese Patent JP2007536938
Kind Code:
A
Abstract:
This invention relates to methods of inhibiting the growth of cells, in particular cancer cells, that overexpress Wnt2. The methods comprise contacting the cell with an agent that binds to Wnt2 mRNA or Wnt2 protein, interferes with Wnt2 signaling or inhibits binding of the Wnt2 protein to another protein, such as a Frizzled receptor.
Inventors:
You Lin
Feipou
Shu Qi Dong
Jablon's David M.
Feipou
Shu Qi Dong
Jablon's David M.
Application Number:
JP2007513458A
Publication Date:
December 20, 2007
Filing Date:
May 16, 2005
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
C12N15/09; A61K31/7105; A61K39/395; A61K48/00; A61P1/04; A61P1/16; A61P1/18; A61P5/14; A61P11/00; A61P13/08; A61P13/12; A61P15/00; A61P17/00; A61P25/00; A61P35/00; A61P35/02; A61P43/00; C07K7/08; C07K16/18; C07K16/32; C12N15/113; C12P21/06; C12P21/08
Foreign References:
| WO2004032838A2 | 2004-04-22 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi