Title:
レトロウイルスプロテアーゼ阻害剤として有用なリトナビル類似化合物、そのリトナビル類似化合物の製造方法及びそのリトナビル類似化合物の薬学的組成物
Document Type and Number:
Japanese Patent JP2007537166
Kind Code:
A
Abstract:
The present invention describes a new one ritonavir analogous compound that presents significantly superior activity in inhibition of HIV protease. There are also described the usage of the ritonavir analogous compound of the present invention or salt, ester or prodrug thereof as well as the usage of the compound and its pharmaceutical compositions in medicine, particularly, in the treatment of HIV infection, by itself or in combination with others anti-HIV drugs.
Inventors:
Bockelman, Maria Alice
Rosat, Simone Soares
Fuzet, Claudio Roberto
Vernucci, Tiago Boscaro
Barrel, Daniela Cecilia
Oliveira, Kesley Moraes Godinhod
Freitas, Maceus Pudjinad
Rosat, Simone Soares
Fuzet, Claudio Roberto
Vernucci, Tiago Boscaro
Barrel, Daniela Cecilia
Oliveira, Kesley Moraes Godinhod
Freitas, Maceus Pudjinad
Application Number:
JP2007511791A
Publication Date:
December 20, 2007
Filing Date:
May 11, 2005
Export Citation:
Assignee:
Crystallia Produtos Kimikos Pharmachuticos Limiteda
International Classes:
C07D277/28; A61K31/427; A61K45/00; A61P31/18; A61P43/00; C07D277/24
Domestic Patent References:
| JPH04308574A | 1992-10-30 |
Foreign References:
| US5541206A | 1996-07-30 | |||
| US5567823A | 1996-10-22 |
Attorney, Agent or Firm:
Hideo Takino
Sadao Matsumura
Isamu Kakiuchi
Fumio Takino
Sadao Matsumura
Isamu Kakiuchi
Fumio Takino