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Title:
血栓症の治療に有用なP2Y1レセプターのウレアアンタゴニスト
Document Type and Number:
Japanese Patent JP2008500284
Kind Code:
A
Abstract:
The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.

Inventors:
Hang An Jay Chao
Tweldi Fuji
Timothy Harpin
Jack eve loberge
Liu Yaray
Earl Michael Lawrence
Robert pee refus
Charles G. Clark
Kiao Jennifer X
Timur Gyungor
Patrick WSS Ram
Tammy Sea One
Lijan Rule
Alexandre El Rouleux
Karl Tibor
Jill Bootillier
Dora M. Schner
Application Number:
JP2007513296A
Publication Date:
January 10, 2008
Filing Date:
May 11, 2005
Export Citation:
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Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D213/75; A61K31/17; A61K31/381; A61K31/44; A61K31/4425; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/4709; A61K31/496; A61K31/50; A61K31/501; A61K31/5377; A61K31/538; A61K31/661; A61K31/69; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P13/12; C07C275/30; C07C275/32; C07C275/34; C07C275/36; C07C275/40; C07C275/42; C07D213/40; C07D213/89; C07D231/40; C07D231/50; C07D237/22; C07D333/36; C07D401/12; C07D401/14; C07D405/12; C07D405/14; C07D407/12; C07D409/12; C07D409/14; C07D413/12; C07D417/12; C07F5/04; C07F7/18; C07F9/58
Domestic Patent References:
JP2000515846A2000-11-28
JPS6434979A1989-02-06
JPS60149583A1985-08-07
JP2000504722A2000-04-18
JP2001526220A2001-12-18
JPH07188151A1995-07-25
Foreign References:
US6093742A2000-07-25
WO2001025190A12001-04-12
WO1992001697A11992-02-06
WO2004002481A12004-01-08
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Yushiro Tsuboi
Masahiro Nitta