Title:
抗糖尿病活性をもつベンゾ尿素
Document Type and Number:
Japanese Patent JP2008501027
Kind Code:
A
Abstract:
Benzourea compounds of Formula I having aryl-(CH2)x-oxazolidinedione or aryl-(CH2)x-thiazolidinedione substituents on one of the N atoms of the benzourea ring, wherein x is 0 or 1, are PPAR gamma agonists or partial agonists and are useful in the treatment and control of type II diabetes, including hyperglycemia and other symptoms such as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity, that are often associated with type 2 diabetes. I
Inventors:
Riu, Wakeo
Wood, Harold Bee
Lau Poor, Fiona Wai Yui
Wood, Harold Bee
Lau Poor, Fiona Wai Yui
Application Number:
JP2007515386A
Publication Date:
January 17, 2008
Filing Date:
May 26, 2005
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D413/10; A61K31/422; A61K31/423; A61K31/428; A61K45/00; A61P1/04; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P5/28; A61P5/50; A61P9/02; A61P9/10; A61P9/12; A61P9/14; A61P15/00; A61P17/06; A61P19/08; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07D413/14; C07D417/14
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura