Title:
ピロロベンズイミダゾロン及びその抗増殖薬としての使用
Document Type and Number:
Japanese Patent JP2008502709
Kind Code:
A
Abstract:
The invention relates to pyrrolobenzimidazolone compounds of formula (I), wherein A,T and R1 to R3 are defined as in claim 1, which possess tubulin inhibitory activity and are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation and the use thereof for preparing a pharmaceutical composition.
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Inventors:
McConnell Daryl
Steyler Steffen
Christ Bernd
Weir Zernirovsky Ulrike
Maria Impagnatiero
Troy Mathias
Kaufmann Hefner Iris
Garin Chesa Pillar
Schnap Andreas
Steyler Steffen
Christ Bernd
Weir Zernirovsky Ulrike
Maria Impagnatiero
Troy Mathias
Kaufmann Hefner Iris
Garin Chesa Pillar
Schnap Andreas
Application Number:
JP2007517242A
Publication Date:
January 31, 2008
Filing Date:
May 13, 2005
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D487/04; A61K31/4188; A61K31/422; A61K31/427; A61K31/4439; A61K31/454; A61K31/4709; A61K31/496; A61K31/501; A61P1/00; A61P3/10; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P43/00
Domestic Patent References:
| JPS63162692A | 1988-07-06 | |||
| JPS62145083A | 1987-06-29 | |||
| JPH0363264A | 1991-03-19 |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama