Title:
アミノキノリンをQとし、抗生物質残基をAとする混成分子QA、その合成及び抗菌剤としての使用
Document Type and Number:
Japanese Patent JP2008508243
Kind Code:
A
Abstract:
The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q-(Y1)p-(U)p-(Y2)p-A: wherein Q represents an aminoquinoline, (Y1)p(U)p-(Y2)p'' is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.
Inventors:
Muriel Sanchez
Bernard Meuniere
Bernard Meuniere
Application Number:
JP2007523114A
Publication Date:
March 21, 2008
Filing Date:
July 26, 2005
Export Citation:
Assignee:
Palmed Societe Anonymous
Center National de la Recherche Scientific (Se En Ale S)
Center National de la Recherche Scientific (Se En Ale S)
International Classes:
C07D215/56; A61K31/4709; A61K31/496; A61K31/506; A61K31/5377; A61K31/546; A61K31/7048; A61K38/00; A61K45/00; A61P1/00; A61P1/02; A61P1/16; A61P7/00; A61P9/00; A61P11/00; A61P13/02; A61P15/00; A61P17/00; A61P17/02; A61P25/00; A61P27/02; A61P27/16; A61P31/04; A61P43/00; C07D401/12; C07D413/12; C07D499/54; C07D499/64; C07D499/76; C07D501/22; C07D501/24; C07D501/36; C07H17/08; A61K47/22; A61K47/48
Domestic Patent References:
| JP2003183282A | 2003-07-03 | |||
| JPH0193592A | 1989-04-12 | |||
| JPH06179674A | 1994-06-28 | |||
| JPS53121789A | 1978-10-24 | |||
| JPS5359693A | 1978-05-29 | |||
| JPS5176287A | 1976-07-01 | |||
| JPS49125387A | 1974-11-30 |
Foreign References:
| US4404201A | 1983-09-13 |
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro