Title:
生理活性物質を含むバイオミメティック溶液で基体をコートするバイオミメティック法、ならびに骨、結合組織、脂肪組織、および筋組織工学における当該方法および基体の使用
Document Type and Number:
Japanese Patent JP2008509719
Kind Code:
A
Abstract:
The invention relates to a biomimetic process for coating a substrate, particularly a medical device, with a biomimetic composition, which comprises: d) producing batchwise in a closed system an acidified biomimetic composition comprising a saline aqueous mixture containing calcium-, magnesium-, phosphate-, bicarbonate ions and a bioactive substance, e) contacting the substrate with said biomimetic composition and f) storing the biomimetic composition in contact with the substrate and allowing a gradual increase of the pH to occur and to cause precipitation of salts and co-precipitation of the bioactive substance on said substrate and to obtain a coated substrate.
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Inventors:
Riu, Yuelian
Application Number:
JP2007525563A
Publication Date:
April 03, 2008
Filing Date:
August 10, 2005
Export Citation:
Assignee:
Yekimed Age
International Classes:
A61L27/00
Domestic Patent References:
| JP2001525718A | 2001-12-11 | |||
| JP2004230174A | 2004-08-19 | |||
| JP2000093503A | 2000-04-04 | |||
| JP2003325561A | 2003-11-18 | |||
| JP2003521351A | 2003-07-15 | |||
| JP2001525718A | 2001-12-11 | |||
| JP2004230174A | 2004-08-19 |
Foreign References:
| WO2002060507A1 | 2002-08-08 | |||
| WO2002056904A1 | 2002-07-25 | |||
| WO2002060507A1 | 2002-08-08 | |||
| WO2002056904A1 | 2002-07-25 |
Other References:
JPN6011051181; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．５８３-９２
JPN6011051183; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．２９０１-１０
JPN6011051185; Ｊ Ｂｉｏｍｅｄ Ｍａｔｅｒ Ｒｅｓ．， ５７ （２００１） ｐ．１４０-５０
JPN6011051181; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．５８３-９２
JPN6011051183; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．２９０１-１０
JPN6011051185; Ｊ Ｂｉｏｍｅｄ Ｍａｔｅｒ Ｒｅｓ．， ５７ （２００１） ｐ．１４０-５０
JPN6011051183; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．２９０１-１０
JPN6011051185; Ｊ Ｂｉｏｍｅｄ Ｍａｔｅｒ Ｒｅｓ．， ５７ （２００１） ｐ．１４０-５０
JPN6011051181; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．５８３-９２
JPN6011051183; Ｂｉｏｍａｔｅｒｉａｌｓ， ２５ （２００４） ｐ．２９０１-１０
JPN6011051185; Ｊ Ｂｉｏｍｅｄ Ｍａｔｅｒ Ｒｅｓ．， ５７ （２００１） ｐ．１４０-５０
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Ryo Hashimoto
Tetsuya Kazama
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Ryo Hashimoto
Tetsuya Kazama