Title:
粒子の顆粒化方法
Document Type and Number:
Japanese Patent JP2008518942
Kind Code:
A
Abstract:
The invention encompasses a process for granulating particles that produces homogeneous, free flowing, attrition resistant, uniform sized granules. When utilized with active pharmaceutical ingredients, such granules can be further processed into controlled released or taste-masked pharmaceutical formulations. Particularly, the process can be utilized to make an oral granule formulation of etoricoxib for treating pain and inflammation in patients that cannot swallow a tablet, such as young children and the elderly.
Inventors:
Ho, The Yenifar S
Deumont, Hubert
Manchinelli, Christopher
Sielker, Suhas Day
Deumont, Hubert
Manchinelli, Christopher
Sielker, Suhas Day
Application Number:
JP2007539240A
Publication Date:
June 05, 2008
Filing Date:
October 31, 2005
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
A61K31/444; A61K9/16; A61K47/02; A61K47/10; A61K47/32; A61K47/36; A61K47/38; A61K47/42; A61K47/46; A61P29/00; B01J2/00; B01J2/16
Domestic Patent References:
| JP2004506681A | 2004-03-04 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura