Title:
キナーゼ阻害剤として適切なN,N’-ジフェニル尿素誘導体
Document Type and Number:
Japanese Patent JP2008519778
Kind Code:
A
Abstract:
Compounds of the formula (I), in which R1, R3 and X have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.
Inventors:
Hale Zuemann, Gunther
Classia, Haylene
Young whale, Alfret
Lautenberg, Wilfried
Classia, Haylene
Young whale, Alfret
Lautenberg, Wilfried
Application Number:
JP2007540514A
Publication Date:
June 12, 2008
Filing Date:
October 12, 2005
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D471/04; A61K31/519; A61K31/5377; A61P13/08; A61P15/08; A61P17/06; A61P19/02; A61P19/08; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/04; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata