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Title:
N-(ヘテロアリール)-1H-インドール-2-カルボキサミド誘導体及びバニロイドTRPV1受容体リガンドとしてのその使用
Document Type and Number:
Japanese Patent JP2008526820
Kind Code:
A
Abstract:
The invention concerns therapeutic uses of compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation among others as disclosed and specifically claimed.

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Inventors:
Deyubois, Laurent
Evano, Yanik
Malanda, Andre
Application Number:
JP2007549933A
Publication Date:
July 24, 2008
Filing Date:
January 04, 2006
Export Citation:
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Assignee:
Sanofui-Aventice
International Classes:
C07D401/12; A61K31/404; A61K31/428; A61K31/4709; A61K31/538; A61P1/00; A61P11/00; A61P13/00; A61P15/02; A61P17/04; A61P17/06; A61P25/04; A61P27/14; A61P29/00; A61P31/22; A61P37/08; C07D403/12; C07D405/12; C07D413/12; C07D417/12
Domestic Patent References:
JP2002542235A2002-12-10
JP2002515431A2002-05-28
JP2001527066A2001-12-25
JP2001522798A2001-11-20
JPH1036346A1998-02-10
JP2001512119A2001-08-21
JP2002504081A2002-02-05
JP2002500619A2002-01-08
JP2001512119A2001-08-21
JP2002504081A2002-02-05
JP2002500619A2002-01-08
JP2002542235A2002-12-10
JP2002515431A2002-05-28
JP2001527066A2001-12-25
JP2001522798A2001-11-20
JPH1036346A1998-02-10
Foreign References:
WO2002004418A22002-01-17
WO2003068749A12003-08-21
WO2003044014A12003-05-30
WO2004056768A22004-07-08
WO2003044014A12003-05-30
WO2004056768A22004-07-08
WO2002004418A22002-01-17
WO2003068749A12003-08-21
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura



 
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