Title:
カンナビノイドCB2受容体モジュレーターとしての1H-イミダゾール誘導体
Document Type and Number:
Japanese Patent JP2008530179
Kind Code:
A
Abstract:
The invention relates to a group of 1 H-imidazole derivatives which are modulators of cannabinoid CB2 receptors, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said imidazole derivatives, to methods for the preparation of these intermediates, to pharmaceutical compositions containing one or more of these 1 H-imidazole derivatives as active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which cannabinoid CB2 receptors are involved. The compounds have the general formula (I) wherein R1-R4 have the meanings given in the specification.
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Inventors:
Lange, Josephus H.M.
Steuweenberg, Hermann H.
Van Burrito, Bernard Theei
Steuweenberg, Hermann H.
Van Burrito, Bernard Theei
Application Number:
JP2007555612A
Publication Date:
August 07, 2008
Filing Date:
February 16, 2006
Export Citation:
Assignee:
Solvay Pharmaceuticals B.V.
International Classes:
C07D233/90; A61K31/4164; A61K31/4174; A61K31/4178; A61K31/4184; A61K31/427; A61K31/4439; A61K31/454; A61K31/4709; A61K31/496; A61K31/5377; A61K31/55; A61P25/04; A61P43/00; C07D233/64; C07D401/04; C07D401/06; C07D401/12; C07D403/06; C07D403/12; C07D405/04; C07D405/06; C07D405/12; C07D417/04
Attorney, Agent or Firm:
Patent business corporation Odashima patent office
Heikichi Odashima
Heikichi Odashima