Title:
デコリン遺伝子を含む遺伝子伝達システム及びこれを含む薬剤学的抗腫瘍組成物
Document Type and Number:
Japanese Patent JP2008531010
Kind Code:
A
Abstract:
The present invention relates to a novel gene delivery system and recombinant adenovirus comprising the decorin-encoding sequence to enhance transduction efficiency of transgenes, a pharmaceutical anti-tumor composition comprising the recombinant adenovirus, a pharmaceutical composition having improved tissue penetration potency and a pharmaceutical composition for treating a disease or disorder associated with accumulation of excess extracellular matrix.
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Inventors:
YUN,Chaoe-Ok
KIM,Joo Han
KIM,Joo Han
Application Number:
JP2007556977A
Publication Date:
August 14, 2008
Filing Date:
February 24, 2006
Export Citation:
Assignee:
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION YONSEI UNIVERSITY
YUN,Chaoe-Ok
KIM,Joo-Hyun
YUN,Chaoe-Ok
KIM,Joo-Hyun
International Classes:
C12N7/00; A61K31/7088; A61K35/76; A61K48/00; A61P1/16; A61P9/10; A61P11/00; A61P11/16; A61P13/12; A61P17/02; A61P35/00; A61P43/00; C12N15/09
Domestic Patent References:
| JP2008503205A | 2008-02-07 | |||
| JP2003034651A | 2003-02-07 | |||
| JP2003532681A | 2003-11-05 |
Foreign References:
| US6524573B1 | 2003-02-25 |
Attorney, Agent or Firm:
Sakuo Yamaguchi